Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes

IMPORTANCE: Pharmacological enhancers of lipoprotein lipase (LPL) are in preclinical or early clinical development for cardiovascular prevention. Studying whether these agents will reduce cardiovascular events or diabetes risk when added to existing lipid-lowering drugs would require large outcome t...

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書目詳細資料
發表在:JAMA Cardiol
Main Authors: Lotta, Luca A., Stewart, Isobel D., Sharp, Stephen J., Day, Felix R., Burgess, Stephen, Luan, Jian’an, Bowker, Nicholas, Cai, Lina, Li, Chen, Wittemans, Laura B. L., Kerrison, Nicola D., Khaw, Kay-Tee, McCarthy, Mark I., O’Rahilly, Stephen, Scott, Robert A., Savage, David B., Perry, John R. B., Langenberg, Claudia, Wareham, Nicholas J.
格式: Artigo
語言:Inglês
出版: American Medical Association 2018
主題:
Original Investigation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217943/
https://ncbi.nlm.nih.gov/pubmed/30326043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2018.2866
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