Once- versus twice-daily abacavir and lamivudine in African children: the randomised controlled ARROW Trial

BACKGROUND: ART adherence is critical for successful HIV treatment outcomes. Once-daily dosing could improve adherence. Plasma concentrations of once- vs twice-daily abacavir+lamivudine are bioequivalent in children, but no randomised trial has compared virological outcomes. METHODS: Children taking...

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Vydáno v:AIDS
Hlavní autoři: Musiime, Victor, Kasirye, Philip, Naidoo-James, Bethany, Nahirya-Ntege, Patricia, Mhute, Tawanda, Cook, Adrian, Mugarura, Lincoln, Munjoma, Marshall, Thoofer, Navdeep K, Ndashimye, Emmanuel, Nankya, Immaculate, Spyer, Moira J., Thomason, Margaret J., Snowden, Wendy, Gibb, Diana M., Walker, A. Sarah
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217915/
https://ncbi.nlm.nih.gov/pubmed/27064996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001116
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