RDNA-13. VALIDATION OF BEHAVIORAL ANALYSIS ACROSS AGE IN A MOUSE MODEL FOR FUTURE INVESTIGATION OF RADIATION-INDUCED HYPERSOMNOLENCE (RIH) IN PRIMARY BRAIN TUMOR (PBT) PATIENTS

BACKGROUND: Cranial radiation is part of standard PBT treatment with patient age recognized to impact response and toxicity. RIH is one of the most common toxicities. We have reported an association between circadian gene variants and RIH susceptibility. No rodent model for RIH has been validated. T...

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Publicado no:Neuro Oncol
Main Authors: Figiel, Caitlin, Shuboni-Mulligan, Dorela, Armstrong, Terri, Smart, DeeDee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217536/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.928
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