Efficient Synthesis and in Silico Studies of the Benzimidazole Hybrid Scaffold with the Quinolinyloxadiazole Skeleton with Potential α-Glucosidase Inhibitory, Anticoagulant, and Antiplatelet Activities for Type-II Diabetes Mellitus Management and Treating Thrombotic Disorders

[Image: see text] The current study evaluates antidiabetic, anticoagulant, and antiplatelet activity of novel benzimidazole-containing quinolinyl oxadiazoles. These derivatives are synthesized and characterized using spectroscopy (FT-IR, (1)H NMR, and mass spectroscopy) and single-crystal X-ray diff...

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Publicat a:ACS Omega
Autors principals: Bharadwaj, S. Shashidhar, Poojary, Boja, Nandish, Sharath Kumar M., Kengaiah, Jayanna, Kirana, Mugaranja P., Shankar, Madan Kumar, Das, Anupam J., Kulal, Ananda, Sannaningaiah, Devaraja
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217529/
https://ncbi.nlm.nih.gov/pubmed/30411010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01476
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