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Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection

Cellular mosaicism due to monoallelic autosomal expression (MAE), with cell selection during development, is becoming increasingly recognized as prevalent in mammals, leading to interest in understanding its extent and mechanism(s). We report here use of clonal cell lines derived from the CNS of adu...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Branciamore, Sergio, Valo, Zuzana, Li, Min, Wang, Jinhui, Riggs, Arthur D., Singer-Sam, Judith
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217436/
https://ncbi.nlm.nih.gov/pubmed/30322913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808652115
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