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TMIC-44. ASTROCYTE SENESCENCE: A MODEL FOR AGE AND SEX EFFECTS ON GLIOBLASTOMA INCIDENCE

Primary brain tumor incidence rates rise more rapidly in males than females with increasing age. Both pre-neoplastic cells and stromal elements contribute to age-related increases in cancer, and cellular senescence plays a role in the transformation of pre-neoplastic cells. While senescence prevents...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Hill, Cameron, Rhee, Gina, Rubin, Joshua, Broestl, Lauren, Sponagel, Jasmin
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217087/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1103
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