CMET-30. BRAIN METASTASES FROM EGFR-MUTATED NSCLC WHICH HAD ACQUIRED RESISTANCE TO EGFR-TKI. ~LESS-FREQUENT T790M AND PRESERVED RESPONSE TO OTHER TKIs~

BACKGROUND: Despite the favorable response, most brain metastases (MBs) acquire resistance to TKIs. T790M is the most common mechanism and accounts for approximately half of acquired resistance to TKIs. The aim of this study is to clarify the role of T790M in the acquired resistance of BMs, and opti...

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Publicado no:Neuro Oncol
Main Authors: Iuchi, Toshihiko, Sakaida, Tsukasa, Hasegawa, Yuzo, Yoshida, Yasushi, Ashinuma, Hironori, Mizuno, Satoko, Setoguchi, Taiki, Shingoji, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216946/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.242
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