EPID-11. PROGRESSION OF IDH MUTANT GLIOMA AFTER FIRST RECURRENCE: DEVELOPMENT OF A FEASIBLE CLINICAL TRIAL ENDPOINT IN THE RECURRENT SETTING

BACKGROUND: Isocitrate dehydrogenase (IDH) mutant tumors represent a distinct subtype among diffuse gliomas, with improved prognosis compared to grade-matched IDH wild-type tumors. As a basis for clinical trial design of IDH-targeting drugs, we sought to describe outcomes exclusively within the glio...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Miller, Julie, Loebel, Franziska, Arrillaga-Romany, Isabel, Mordes, Daniel, Lelic, Nina, Batchelor, Tracy, Iafrate, A John, Chi, Andrew, Cahill, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216783/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.338
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