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CSIG-37. FOXR2 STABILIZES MYC AND ACTIVATES FAK/SRC SIGNALING IN A DUAL MECHANISM TO PROMOTE TRANSFORMATION IN NEURAL PROGENITOR CELLS

Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNETs) are aggressive, poorly differentiated brain tumors that primarily affect children. Current treatment strategies with severe long-term treatment-related side effects and poor survival rates warrant further study i...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Beckmann, Pauline, Larson, Jon, Larsson, Alex, Ostergaard, Jason, Largaespada, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216769/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.203
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