GENE-25. LOSS OF m(6)A RNA METHYLATION DURING GLIOMA STEM CELL DIFFERENTIATION IS REGULATED BY MIRNAS AND PROMOTES TRANSLATION EFFICIENCY

The dynamic and reversible N(6)-methyladenoside (m(6)A) affects eukaryotic mRNA localization, stability, splicing and translation. However, the role of m(6)A RNA methylation in the regulation of translation efficiency in human cancer cells is largely unknown. Here, using ribosome profiling, integrat...

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發表在:Neuro Oncol
Main Authors: Zepecki, John, Fajardo, Eduardo, Snyder, Kristin, Guetta-Terrier, Charlotte, Tang, Oliver, Sarkar, Atom, Fiser, Andras, Toms, Steven
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216761/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.451
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