IMMU-63. IDH1 MUTATION REGULATE MYELOID CELLS PLASTICITY MEDIATING ANTI-GLIOMA IMMUNOTHERAPY

Molecular characterization studies have illustrated that mutation in isocitrate dehydrogenase (mIDH1) enzyme, which is present in most patients with low grade glioma (LGG) and secondary glioma is correlated with better prognosis and survival [1]. We hypothesize that mIDH1 impacts tumor immunity by a...

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Publié dans:Neuro Oncol
Auteurs principaux: Alghamri, Mahmoud, Kamran, Neha, Nunez, Felipe, Kadiyala, Padma, Zhang, Li, Avvari, Ruthvik, Lowenstein, Pedro, Castro, Maria
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216656/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.566
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