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GENE-19. GAINING A BETTER UNDERSTANDING OF DNA METHYLATION FEATURES ASSOCIATED WITH SEX DIFFERENCES IN GLIOBLASTOMA

Glioblastoma displays strong sexual dimorphism with male having an increased prevalence and poorer prognosis. While sex based methylation differences in the MGMT promoter have been described in GBM patients, we expanded on these findings with a full genome interrogation of sex-based DNA methylation...

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Publicado en:Neuro Oncol
Autores principales: Stetson, Lindsay, Lathia, Justin, Rubin, Joshua, Connor, James, Waite, Kristin, Berens, Michael, Barnholtz-Sloan, Jill
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216638/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.445
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