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DDIS-17. MULTI-LEVEL DRUG DEVELOPMENT PIPELINE FOR THE DISCOVERY OF TUMOR MICROTUBE TARGETING DRUGS

Tumor microtubes (TMs), which are ultra-thin and long cellular protrusions extended by glioma cells, have emerged as a novel mechanism of glioma cell growth, invasion and interconnection with consecutive therapy resistance. So far, few molecular drivers of TM formation and function (Gap43, Cx43, Tty...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jung, Erik, Osswald, Matthias, Koch, Philipp, Wick, Wolfgang, Winkler, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216629/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.296
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