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Spatial Vulnerabilities of the Escherichia coli Genome to Spontaneous Mutations Revealed with Improved Duplex Sequencing

Investigation of spontaneous mutations by next-generation sequencing technology has attracted extensive attention lately due to the fundamental roles of spontaneous mutations in evolution and pathological processes. However, these studies only focused on the mutations accumulated through many genera...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Zhang, Xiaolong, Zhang, Xuehong, Zhang, Xia, Liao, Yuwei, Song, Luyao, Zhang, Qingzheng, Li, Peiying, Tian, Jichao, Shao, Yanyan, AI-Dherasi, Aisha Mohammed, Li, Yulong, Liu, Ruimei, Chen, Tao, Deng, Xiaodi, Zhang, Yu, Lv, Dekang, Zhao, Jie, Chen, Jun, Li, Zhiguang
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216599/
https://ncbi.nlm.nih.gov/pubmed/30076202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301345
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