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Detecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method
The genetic etiology of many complex diseases is highly heterogeneous. A complex disease can be caused by multiple mutations within the same gene or mutations in multiple genes at various genomic loci. Although these disease-susceptibility mutations can be collectively common in the population, they...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216585/ https://ncbi.nlm.nih.gov/pubmed/30104420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301266 |
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