IMMU-55. IMMUNOMODULATORY IL-7 AND IL-12-EXPRESSING MSCs INDUCE LONG-TERM SURVIVAL AND IMMUNITY IN SYNGENEIC INTRACEREBRAL GLIOBLASTOMA MODELS

Mesenchymal stem cells (MSCs) show an inherent brain tumor cell tropism that can be exploited for targeted delivery of therapeutic genes to invasive glioma. We assessed whether a motile MSC-based local immunomodulation is able to overcome the immunosuppressive glioblastoma microenvironment and to in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Mohme, Malte, Maire, Cecile, Geumann, Ulf, Dührsen, Lasse, Schliffke, Simon, Fita, Krystian, Binder, Mascha, Lamszus, Katrin, Guenther, Christine, Westphal, Manfred, Hermann, Felix, Schmidt, Nils Ole
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216557/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.558
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