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DRES-15. GSK3 BETA AND hnRNPA1 (RNA BINDING PROTEIN) COOPERATES WITH cMyc TRANSCRIPTIONAL REGULATOR, ANTAGONIZES GSK3 ALPHA UNDER THERAPEUTIC STRESS
Oncogenic cooperation activity tends these glioma cells to acquire drug resistance. Where GSK3 beta isoform cooperates cMyc antagonizes GSK3 alpha isoform. Down regulated expression of GSK3 alpha cooperates elevated hnRNPA1 expression, evolving glioma development. Occurrence of hnRNPA1 dependent alt...
Tallennettuna:
| Julkaisussa: | Neuro Oncol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216552/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.322 |
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