STEM-06. A DRAFT SINGLE-CELL ATLAS OF HUMAN GLIOBLASTOMA REVEALS SPATIAL AND DIFFERENTIATION GRADIENTS OF STEM-LIKE CELLS

Glioblastoma (GBM) stem-like cells (GSCs) expressing markers of the proneural (e.g. OLIG2, DLL3) and mesenchymal (e.g. CHI3L1(YKL-40), CD44) GBM molecular-subtypes have been described. However, it is unknown if these two GSC types are sufficient to generate the spectrum of cellular heterogeneity obs...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mueller, Soeren, Bhaduri, Aparna, DiLullo, Elizabeth, Yagnik, Garima, Lim, Daniel, Aghi, Manish, Kriegstein, Arnold, Diaz, Aaron
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216520/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1013
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