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Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Cyclosporine-A via Suppression of Mitochondrial DNA

BACKGROUND: Lipopolysaccharide (LPS) is generally associated with sepsis, which causes multiple system injuries and systemic inflammatory response. Mitochondrial DNA (mtDNA) is of great importance in mediation of inflammation. The aim of this study was to investigate the protective profiles of Cyclo...

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Bibliografiske detaljer
Udgivet i:Med Sci Monit
Main Authors: Xiao, Zhenghua, Jia, Bangsheng, Zhao, Xueshan, Bi, Siwei, Meng, Wei
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216435/
https://ncbi.nlm.nih.gov/pubmed/30367813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.909909
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