ACTR-43. OPEN-LABEL PHASE 1 CLINICAL TRIAL TESTING PERSONALIZED AND TARGETED SKULL REMODELING SURGERY TO MAXIMIZE TTFIELDS INTENSITY FOR RECURRENT GLIOBLASTOMA – INTERIM ANALYSIS AND SAFETY ASSESSMENT (OPTIMALTTF-1)

BACKGROUND: We present a pre-specified interim analysis of an ongoing open-label, phase-1 IST (NCT02893137) testing safety/efficacy of a new rGBM treatment. The intervention combines personalized skull-remodeling (SR) surgery with TTFields and best-choice chemotherapy. SR-surgery involves minor cran...

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Pubblicato in:Neuro Oncol
Autori principali: Korshoej, Anders, Lukacova, Slavka, Sørensen, Jens Christian, Hansen, Frederik Lundgaard, Mikic, Nikola, Thielscher, Axel, Stigaard Cortnum, Søren Ole, Guldberg, Trine Lignell, Ramshad-Lassen, Yasmin, Rahbek, Christian, Eg Severinsen, Kåre, von Oettingen, Gorm
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216378/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.075
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