TMIC-07. HYPOXIC MICROENVIRONMENT CONFERS SPECIFIC ALTERATIONS IN DNA METHYLATION PROFILES IN GLIOBLASTOMA

High cellularity and poorly organized tumour vasculature in high-grade gliomas leads to insufficient blood supply, hypoxic areas, and ultimately to the formation of necrosis. Thus, hypoxia is a hallmark of malignant glioma microenvironment and it is associated with aggressive tumor behavior such as...

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Publicado no:Neuro Oncol
Main Authors: Mansouri, Sheila, Velasquez, Carlos, Karimi, Shirin, Nassiri, Farshad, Mamatjan, Yasin, Singh, Olivia, Metcalf, Julie, Li, Mira, Suppiah, Suganth, Mansouri, Alireza, Aldape, Kenneth, Zadeh, Gelareh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216332/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1067
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