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TMIC-07. HYPOXIC MICROENVIRONMENT CONFERS SPECIFIC ALTERATIONS IN DNA METHYLATION PROFILES IN GLIOBLASTOMA
High cellularity and poorly organized tumour vasculature in high-grade gliomas leads to insufficient blood supply, hypoxic areas, and ultimately to the formation of necrosis. Thus, hypoxia is a hallmark of malignant glioma microenvironment and it is associated with aggressive tumor behavior such as...
שמור ב:
| הוצא לאור ב: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216332/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1067 |
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