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PATH-01. DEVELOPMENT OF A SENSITIVE MULTIPLEX ASSAY FOR DETECTION OF MUTATIONS IN IDH1 AND IDH2
Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are the most frequently mutated metabolic genes in human cancer. They encode cytosolic and mitochondrial enzymes that catalyze the conversion of isocitrate to a-ketoglutarate (αKG), a key component in metabolic and cellular pathways including the Kreb...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216322/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.657 |
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