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IMMU-31. DYSFUNCTIONAL STING PATHWAY SIGNALING COMPROMISES INNATE IMMUNITY IN GLIOBLASTOMA

BACKGROUND: Stimulator of interferon genes (STING), a protein located in the endoplasmic reticulum, is a key mediator of innate immune response to non-CpG cytosolic DNA. Intact STING has been shown to be involved in the induction of the innate antitumor response in Glioblastoma (GBM). Upon sensing c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bowie, Michelle, Ashley, David, Hostettler, Janell, Brown, Michael, Bryant, Jeffrey, Bigner, Darell, Gromeier, Matthias, Nair, Smita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216295/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.534
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