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IMMU-31. DYSFUNCTIONAL STING PATHWAY SIGNALING COMPROMISES INNATE IMMUNITY IN GLIOBLASTOMA
BACKGROUND: Stimulator of interferon genes (STING), a protein located in the endoplasmic reticulum, is a key mediator of innate immune response to non-CpG cytosolic DNA. Intact STING has been shown to be involved in the induction of the innate antitumor response in Glioblastoma (GBM). Upon sensing c...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216295/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.534 |
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