ACTR-19. A MULTICENTER PILOT PHASE II STUDY OF CONTINUING TMZ WITH THE ADDITION OF DISULFIRAM AND COPPER FOR REFRACTORY GLIOBLASTOMA

BACKGROUND: Preclinical studies have suggested promising activity for the combination of disulfiram and copper (DSF/Cu) against glioblastoma (GBM) including re-sensitization to temozolomide (TMZ). A previous phase I study demonstrated the safety of combining DSF/Cu with adjuvant TMZ for newly diagno...

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Vydáno v:Neuro Oncol
Hlavní autoři: Huang, Jiayi, Chaudhary, Rehka, Cohen, Adam, Fink, Karen, Godlust, Samuel, Boockvar, John, Chinnaiyan, Prakash, Marcus, Stephen, Campian, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216168/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.053
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