Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

Previous work from our group showed that tamoxifen, an oral drug that has been in use for the treatment of breast cancer for over 40 years, is active both in vitro and in vivo against several species of Leishmania, the etiological agent of leishmaniasis. Using a combination of metabolic labeling wit...

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Dettagli Bibliografici
Pubblicato in:Int J Parasitol Drugs Drug Resist
Autori principali: Trinconi, Cristiana T., Miguel, Danilo C., Silber, Ariel M., Brown, Christopher, Mina, John G.M., Denny, Paul W., Heise, Norton, Uliana, Silvia R.B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Regular article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216108/
https://ncbi.nlm.nih.gov/pubmed/30399513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.10.007
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