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Simvastatin Protects Heart from Pressure Overload Injury by Inhibiting Excessive Autophagy

Cardiac hypertrophy is an independent predictor of cardiovascular morbidity and mortality. To identify the mechanisms by which simvastatin inhibits cardiac hypertrophy induced by pressure overload, we determined effects of simvastatin on 14-3-3 protein expression and autophagic activity. Simvastatin...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Su, Feifei, Shi, Miaoqian, Zhang, Jian, Zheng, Qiangsun, Zhang, Dongwei, Zhang, Wei, Wang, Haichang, Li, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216062/
https://ncbi.nlm.nih.gov/pubmed/30443172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.28106
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