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Simvastatin Protects Heart from Pressure Overload Injury by Inhibiting Excessive Autophagy
Cardiac hypertrophy is an independent predictor of cardiovascular morbidity and mortality. To identify the mechanisms by which simvastatin inhibits cardiac hypertrophy induced by pressure overload, we determined effects of simvastatin on 14-3-3 protein expression and autophagic activity. Simvastatin...
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| Pubblicato in: | Int J Med Sci |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ivyspring International Publisher
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216062/ https://ncbi.nlm.nih.gov/pubmed/30443172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.28106 |
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