Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term Cultures

Human Mesenchymal Stem Cells (hMSCs) undergo senescence in lifespan. In most clinical trials, hMSCs experience long-term expansion ex vivo to increase cell number prior to transplantation, which unfortunately leads to cell senescence, hampering post-transplant outcomes. Hydrogen peroxide (H(2)O(2))...

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Bibliografiska uppgifter
I publikationen:Int J Med Sci
Huvudupphovsmän: Facchin, Federica, Bianconi, Eva, Romano, Miriam, Impellizzeri, Alessia, Alviano, Francesco, Maioli, Margherita, Canaider, Silvia, Ventura, Carlo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216057/
https://ncbi.nlm.nih.gov/pubmed/30443170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.27181
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