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Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer

BACKGROUND: PIM1, a serine/threonine kinase, plays an essential role in tumorigenesis of multiple types of tumors. However, the expression pattern and functions of PIM1 in gallbladder cancer (GBC) remain largely unknown. MATERIALS AND METHODS: Immunohistochemistry, quantitative real-time PCR, and we...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Xue, Chen, He, Yuting, Hu, Qiuyue, Yu, Yan, Chen, Xiaolong, Chen, Jianan, Ren, Fang, Li, Juan, Ren, Zhigang, Cui, Guangying, Sun, Ranran
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215917/
https://ncbi.nlm.nih.gov/pubmed/30464610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S184381
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