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Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Hepatocellular carcinoma (HCC) accounts for a large proportion of liver cancer cases and has an extremely poor prognosis. Therefore, novel innovative therapies for HCC are strongly desired. As gene therapy tools for HCC, 2 hepatic transcription factors (TF), HNF4A and HNF1A, have been used to suppre...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Takashima, Yasuo, Horisawa, Kenichi, Udono, Miyako, Ohkawa, Yasuyuki, Suzuki, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215883/
https://ncbi.nlm.nih.gov/pubmed/30220099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13798
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