Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele

Omphalocele is a human congenital anomaly in ventral body wall closure and may be caused by impaired formation of the primary abdominal wall (PAW) and/or defects in abdominal muscle development. Here, we report that mice doubly deficient in homeobox genes Six4 and Six5 showed the same ventral body w...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Takahashi, Masanori, Tamura, Masaru, Sato, Shigeru, Kawakami, Kiyoshi
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215434/
https://ncbi.nlm.nih.gov/pubmed/30237319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.034611
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