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Interactions between Triterpenes and a P-I Type Snake Venom Metalloproteinase: Molecular Simulations and Experiments

Small molecule inhibitors of snake venom metalloproteinases (SVMPs) could provide a means to rapidly halt the progression of local tissue damage following viperid snake envenomations. In this study, we examine the ability of candidate compounds based on a pentacyclic triterpene skeleton to inhibit S...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Preciado, Lina María, Pereañez, Jaime Andrés, Azhagiya Singam, Ettayapuram Ramaprasad, Comer, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215199/
https://ncbi.nlm.nih.gov/pubmed/30274214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10100397
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