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Drug-induced dysphoria is enhanced following prolonged cocaine abstinence and dynamically tracked by nucleus accumbens neurons
Negative reinforcement models postulate that addicts use drugs to alleviate negative affective states (e.g., dysphoria) associated with withdrawal. In a preclinical model, rats exhibit negative affect to a normally rewarding tastant when it predicts impending, but delayed cocaine, and nucleus accumb...
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| Publicado no: | Addict Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6214800/ https://ncbi.nlm.nih.gov/pubmed/29717793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12627 |
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