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A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development

Hundreds of thousands of cis-regulatory DNA sequences are predicted in vertebrate genomes, but unlike genes themselves, few have been characterized at the functional level or even unambiguously paired with a target gene. Here we serendipitously identified and started investigating the first reported...

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Dettagli Bibliografici
Pubblicato in:Dev Biol
Autori principali: Tarchini, Basile, Longo-Guess, Chantal, Tian, Cong, Tadenev, Abigail L.D., Devanney, Nicholas, Johnson, Kenneth R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214362/
https://ncbi.nlm.nih.gov/pubmed/30217595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.09.011
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