A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4

Evolutionary forces select genetic variants that allow adaptation to environmental stresses. The genomes of centenarian populations could recapitulate the evolutionary adaptation model and reveal the secrets of disease resistance shown by these individuals. Indeed, longevity phenotype is supposed to...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Villa, Francesco, Carrizzo, Albino, Ferrario, Anna, Maciag, Anna, Cattaneo, Monica, Spinelli, Chiara Carmela, Montella, Francesco, Damato, Antonio, Ciaglia, Elena, Puca, Annibale Alessandro
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214030/
https://ncbi.nlm.nih.gov/pubmed/30347645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103229
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