A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4

Evolutionary forces select genetic variants that allow adaptation to environmental stresses. The genomes of centenarian populations could recapitulate the evolutionary adaptation model and reveal the secrets of disease resistance shown by these individuals. Indeed, longevity phenotype is supposed to...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Villa, Francesco, Carrizzo, Albino, Ferrario, Anna, Maciag, Anna, Cattaneo, Monica, Spinelli, Chiara Carmela, Montella, Francesco, Damato, Antonio, Ciaglia, Elena, Puca, Annibale Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214030/
https://ncbi.nlm.nih.gov/pubmed/30347645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103229
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