Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an active component of Chinese herbs, and is effective against leukemia, lung cancer, colon cancer, pancreatic cancer, and...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kim, Young-Seon, Lee, Yoon-Mi, Oh, Taek-In, Shin, Dong Hoon, Kim, Geon-Hee, Kan, Sang-Yeon, Kang, Hyeji, Kim, Ji Hyung, Kim, Byeong Mo, Yim, Woo Jong, Lim, Ji-Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213641/
https://ncbi.nlm.nih.gov/pubmed/30321984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103127
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