Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an active component of Chinese herbs, and is effective against leukemia, lung cancer, colon cancer, pancreatic cancer, and...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kim, Young-Seon, Lee, Yoon-Mi, Oh, Taek-In, Shin, Dong Hoon, Kim, Geon-Hee, Kan, Sang-Yeon, Kang, Hyeji, Kim, Ji Hyung, Kim, Byeong Mo, Yim, Woo Jong, Lim, Ji-Hong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213641/
https://ncbi.nlm.nih.gov/pubmed/30321984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103127
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