Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS)

Rheumatoid arthritis (RA) is a common autoimmune disease. The inflammation in joint tissue and system endanger the human health seriously. Methotrexate have exhibited a satisfactory therapeutic effect in clinical practice. The aim of this research was to establish the pharmacological mechanism of me...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Pang, Zhiqiang, Wang, Guoqiang, Ran, Nan, Lin, Hongqiang, Wang, Ziyan, Guan, Xuewa, Yuan, Yuze, Fang, Keyong, Liu, Jinping, Wang, Fang
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212996/
https://ncbi.nlm.nih.gov/pubmed/30249062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19102894
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