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Addressing the Issue of Tetrodotoxin Targeting
This review is devoted to the medical application of tetrodotoxin (TTX), a potent non-protein specific blocker of voltage-gated sodium (NaV) channels. The selectivity of action, lack of affinity with the heart muscle NaV channels, and the inability to penetrate the blood–brain barrier make this toxi...
Uloženo v:
| Vydáno v: | Mar Drugs |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212850/ https://ncbi.nlm.nih.gov/pubmed/30261623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16100352 |
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