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Addressing the Issue of Tetrodotoxin Targeting

This review is devoted to the medical application of tetrodotoxin (TTX), a potent non-protein specific blocker of voltage-gated sodium (NaV) channels. The selectivity of action, lack of affinity with the heart muscle NaV channels, and the inability to penetrate the blood–brain barrier make this toxi...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Melnikova, Daria I., Khotimchenko, Yuri S., Magarlamov, Timur Yu.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212850/
https://ncbi.nlm.nih.gov/pubmed/30261623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16100352
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