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A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression

DNA damaging agents cause a variety of lesions, of which DNA double-strand breaks (DSBs) are the most genotoxic. Unbiased approaches aimed at investigating the relationship between the number of DSBs and outcome of the DNA damage response have been challenging due to the random nature in which damag...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: van den Berg, Jeroen, G. Manjón, Anna, Kielbassa, Karoline, Feringa, Femke M, Freire, Raimundo, Medema, René H
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212793/
https://ncbi.nlm.nih.gov/pubmed/30184135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky786
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