Modulation of Antibody Responses to the V1V2 and V3 Regions of HIV-1 Envelope by Immune Complex Vaccines

Prophylactic HIV vaccines must elicit antibodies (Abs) against the virus envelope glycoproteins (Env) to effectively prevent HIV infection. We investigated a vaccine platform that utilizes immune complexes made of Env proteins gp120 and monoclonal Abs (mAbs) against different gp120 epitopes. We prev...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Hioe, Catarina E., Kumar, Rajnish, Upadhyay, Chitra, Jan, Muzafar, Fox, Alisa, Itri, Vincenza, Peachman, Kristina K., Rao, Mangala, Liu, Lily, Lo, Nathan C., Tuen, Michael, Jiang, Xunqing, Kong, Xiang-Peng, Zolla-Pazner, Susan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212562/
https://ncbi.nlm.nih.gov/pubmed/30416503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02441
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