Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis

The intellectual disability gene, Sox11, encodes for a critical neurodevelopmental transcription factor with functions in precursor survival, neuronal fate determination, migration and morphogenesis. The mechanisms regulating SOX11’s activity remain largely unknown. Mass spectrometric analysis uncov...

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Publicado no:Sci Rep
Main Authors: Balta, Elli-Anna, Schäffner, Iris, Wittmann, Marie-Theres, Sock, Elisabeth, von Zweydorf, Felix, von Wittgenstein, Julia, Steib, Kathrin, Heim, Birgit, Kremmer, Elisabeth, Häberle, Benjamin Martin, Ueffing, Marius, Lie, Dieter Chichung, Gloeckner, Christian Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212486/
https://ncbi.nlm.nih.gov/pubmed/30385877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34480-x
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