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Integrating in vitro experiments with in silico approaches for Glioblastoma invasion: the role of cell-to-cell adhesion heterogeneity

Glioblastoma cells adopt migration strategies to invade into the brain parenchyma ranging from individual to collective mechanisms, whose role and dynamics are not yet fully understood. In this work, we explore Glioblastoma heterogeneity and recapitulate its invasive patterns both in vitro, by utili...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Oraiopoulou, M.-E., Tzamali, E., Tzedakis, G., Liapis, E., Zacharakis, G., Vakis, A., Papamatheakis, J., Sakkalis, V.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212459/
https://ncbi.nlm.nih.gov/pubmed/30385804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34521-5
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