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Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis

Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With our case-control study we aimed to identify which chromatin-modifying enzymes could be involved in the pathology of postmenopausal osteoporosis...

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書目詳細資料
發表在:Sci Rep
Main Authors: Vrtačnik, Peter, Zupan, Janja, Mlakar, Vid, Kranjc, Tilen, Marc, Janja, Kern, Barbara, Ostanek, Barbara
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212423/
https://ncbi.nlm.nih.gov/pubmed/30385847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34255-4
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