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Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis

Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With our case-control study we aimed to identify which chromatin-modifying enzymes could be involved in the pathology of postmenopausal osteoporosis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vrtačnik, Peter, Zupan, Janja, Mlakar, Vid, Kranjc, Tilen, Marc, Janja, Kern, Barbara, Ostanek, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212423/
https://ncbi.nlm.nih.gov/pubmed/30385847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34255-4
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