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Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis

CD98 has been implicated in the experimental model of inflammatory bowel disease. We have previously shown that IEC-specific overexpression of CD98 mediates intestinal inflammation and intestinal epithelial barrier dysfunction. Mice overexpressing CD98 exhibited severe colitis and a greater suscepti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Han, Moon K., Baker, Mark, Zhang, Yuchen, Yang, Chunhua, Zhang, Mingzhen, Garg, Pallavi, Viennois, Emilie, Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212412/
https://ncbi.nlm.nih.gov/pubmed/30385787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34474-9
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