Exosomes Derived dystrophin from Allograft Myogenic Progenitors Improve Cardiac Function in Duchenne Muscular Dystrophic Mice

Progressive cardiomyocyte loss in Duchenne muscular dystrophy (DMD) leads to cardiac fibrosis, cardiomyopathy and eventually heart failure. In the present study, we observed that myogenic progenitor cells (MPC) carry mRNA for the dystrophin gene. We tested whether cardiac function can be improved in...

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Publicado en:J Cardiovasc Transl Res
Main Authors: Su, Xuan, Jin, Yue, Shen, Yan, Ju, Chengwei, Cai, Jingwen, Liu, Yutao, Kim, Il-man, Wang, Yu, Yu, Hong, Weintraub, Neal L., Jiang, Meng, Tang, Yaoliang
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212302/
https://ncbi.nlm.nih.gov/pubmed/30155598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-018-9826-9
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