Chromosome assembly of large and complex genomes using multiple references

Despite the rapid development of sequencing technologies, the assembly of mammalian-scale genomes into complete chromosomes remains one of the most challenging problems in bioinformatics. To help address this difficulty, we developed Ragout 2, a reference-assisted assembly tool that works for large...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Kolmogorov, Mikhail, Armstrong, Joel, Raney, Brian J., Streeter, Ian, Dunn, Matthew, Yang, Fengtang, Odom, Duncan, Flicek, Paul, Keane, Thomas M., Thybert, David, Paten, Benedict, Pham, Son
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211643/
https://ncbi.nlm.nih.gov/pubmed/30341161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.236273.118
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