A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Gliomas comprise heterogeneous malignant glial and stromal cells. While blood vessel co-option is a potential mechanism to escape anti-angiogenic therapy, the relevance of glial phenotype in this process is unclear. We show that Olig2(+) oligodendrocyte precursor-like glioma cells invade by single-c...

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Gepubliceerd in:Cancer Cell
Hoofdauteurs: Griveau, Amelie, Seano, Giorgio, Shelton, Samuel J., Kupp, Robert, Jahangiri, Arman, Obernier, Kirsten, Krishnan, Shanmugarajan, Lindberg, Olle R., Yuen, Tracy J., Tien, An-Chi, Sabo, Jennifer K., Wang, Nancy, Chen, Ivy, Kloepper, Jonas, Larrouquere, Louis, Ghosh, Mitrajit, Tirosh, Itay, Huillard, Emmanuelle, Alvarez-Buylla, Arturo, Oldham, Michael C., Persson, Anders I., Weiss, William A., Batchelor, Tracy T., Stemmer-Rachamimov, Anat, Suvà, Mario L., Phillips, Joanna J., Aghi, Manish K., Mehta, Shwetal, Jain, Rakesh K., Rowitch, David H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211172/
https://ncbi.nlm.nih.gov/pubmed/29681511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.020
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