Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis

In the CellSearch(®) system, blood is immunomagnetically enriched for epithelial cell adhesion molecule (EpCAM) expression and cells are stained with the nucleic acid dye 4′6-diamidino-2-phenylindole (DAPI), Cytokeratin-PE (CK), and CD45-APC. Only DAPI+/CK+ objects are presented to the operator to i...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: de Wit, Sanne, Zeune, Leonie L., Hiltermann, T. Jeroen N., Groen, Harry J. M., van Dalum, Guus, Terstappen, Leon W. M. M.
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210778/
https://ncbi.nlm.nih.gov/pubmed/30308977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100377
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