Gap Junction Intercellular Communication Positively Regulates Cisplatin Toxicity by Inducing DNA Damage through Bystander Signaling

The radiation-induced bystander effect (RIBE) can increase cellular toxicity in a gap junction dependent manner in unirradiated bystander cells. Recent reports have suggested that cisplatin toxicity can also be mediated by functional gap junction intercellular communication (GJIC). In this study usi...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Arora, Sanjeevani, Heyza, Joshua R., Chalfin, Elaine C., Ruch, Randall J., Patrick, Steve M.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210410/
https://ncbi.nlm.nih.gov/pubmed/30279363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100368
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