Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data

Sequential courses of anticancer target therapy lead to selection of drug-resistant cells, which results in continuous decrease of clinical response. Here we present a new approach for predicting effective combinations of target drugs, which act in a synergistic manner. Synergistic combinations of d...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Sorokin, Maxim, Kholodenko, Roman, Suntsova, Maria, Malakhova, Galina, Garazha, Andrew, Kholodenko, Irina, Poddubskaya, Elena, Lantsov, Dmitriy, Stilidi, Ivan, Arhiri, Petr, Osipov, Andreyan, Buzdin, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209915/
https://ncbi.nlm.nih.gov/pubmed/30274248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100365
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