Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling

BACKGROUND: In rodent models, chronic exposure to cannabis’ psychoactive ingredient, Δ(9)-tetrahydrocannabinol, during adolescence leads to abnormal behavior in adulthood. In female rats, this maladaptive behavior is characterized by endophenotypes for depressive-like and psychotic-like disorders as...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Cuccurazzu, Bruna, Zamberletti, Erica, Nazzaro, Cristiano, Prini, Pamela, Trusel, Massimo, Grilli, Mariagrazia, Parolaro, Daniela, Tonini, Raffaella, Rubino, Tiziana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Regular Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209859/
https://ncbi.nlm.nih.gov/pubmed/29982505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy057
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